In this section, you will be touched by the emotional stories of families whose lives have been permanently altered by the flu. A diverse range of families from across the U.S. have been brought together by the tragic loss of a child from the flu or by a child who has experienced medical complications from the virus - families who have banded together to heal.

Here you'll learn about a four-year-old girl who went to bed with mild flu-like symptoms, never to wake up; a six-month-old baby boy who died only 30 hours after showing his first symptoms of being sick; and a seemingly healthy 15-year-old who, after baseball team tryouts, began to show flu-like symptoms. Only 24 hours later his heart stopped beating. Sadly, these cases are only a few of many you will read about in this section.

Read about our children by clicking on their names to the left of this page.

On January 5, 2002, 14-month-old James and his twin brother, Robbie, spent the afternoon with their parents at the Boston Children's Museum where they were visiting from New York City.

James and Robbie both began to run a fever later that day. The following day, the coughing and fevers continued so they drove home to New York City that evening with bottles of medicine and a humidifier. That night was rough as James and Robbie were both up almost the entire night and appeared uncomfortable. Their mother gave James a bath to help bring down his fever, but by early morning his breathing seemed labored. James was also wheezing (which was not present in Robbie). His mother brought James to the pediatrician, who in turn had him rushed to the emergency room for what they thought would result in oxygen treatments. Approximately 90 minutes later, on January 7, 2002, James died at the hospital.

The autopsy revealed that James had influenza and a bronchial virus; however, he had no other illnesses or risk factors. James had not been vaccinated against the flu because at the time the Centers for Disease Control and Prevention did not recommend that children his age get vaccinated. Now, every year, James' whole family gets vaccinated against the flu, including his twin brother, Robbie.

On the morning of November 2, 2009, previously healthy 7-year-old Joseph "Joey" Jonathan Holt was sent home from school with a 102 degree fever, but showed no other symptoms of illness. Joey had a strong appetite and seemed like his normal, vivacious self, unstoppable and full of life. Because he had to be fever free for 24 hours before returning to school, Joey stayed home the next day. He was fine throughout the day and spent time writing his Christmas list, playing with his toys and watching movies.

However, the next morning, on November 4, Joey woke up pale and lethargic. He had no appetite and would not drink or eat. Joey spent all day with his mother resting on the couch, being cuddled and loved. During this time his brother, Jeffrey, started developing a slight cough; however, it was nothing to alarm his mother about so Jeffrey went to school. But, later that afternoon, Jeffrey's school called and suggested he be seen by his doctor because he was running a fever of 103 degrees. His mother picked up Jeffrey from school and took both boys to the doctor. After a thorough evaluation, the doctor concluded that Joey had influenza and Jeffrey had a common cold. Their doctor prescribed lots of liquids for Joey and medicine for Jeffrey.

Later that evening Joey became inconsolable, pale and very cold. He wanted nothing more than for his mother to hold him and love him. Joey did not sleep at all that night.

In the early morning hours of November 5, Joey's parents decided that they had done their very best to help him and couldn't do anything more. His mother called 911. Joey was transported to the hospital in an ambulance, but suffered a heart attack en route. Joey was pronounced deceased about an hour later.

Joey's brother, Jeffrey, was also hospitalized that morning and admitted for a week because of similar symptoms. The doctor assumed that Jeffrey also had H1N1 influenza; however, because the proper blood tests were not conducted, his parents will never know.

Preliminary reports revealed the cause of Joey's death was from complications of H1N1 influenza. Joey had not been vaccinated against H1N1 because at the time the vaccine was not available in his community, and his mother was not informed enough to make a decision about whether or not to vaccinate her children. Since Joey's death, the entire family has received the H1N1 vaccine, as well as the seasonal flu vaccine, and has vowed to get vaccinated every year moving forward.

Joey's mother has formed The Joey Holt Foundation in an effort to heighten public awareness and offer educational seminars on the severity of influenza. She also plans on helping other families who have experienced the loss of a child due to influenza. Joey's mother is currently writing a book outlining the life she and her family shared with Joey.

On December 24, 2003, 5½-month-old Marques Jackson, Jr. came down with a fever and a runny nose – symptoms of what his family thought was just a common cold. After a visit to the doctor, it was determined that Marques had influenza. Over the next 24 hours, the severity of his symptoms progressed. Marques began having trouble breathing so his parents called 911. As Marques was being rushed to the hospital he suffered from several small strokes. Marques died in the hospital from complications of influenza on December 28, 2003, just four days after his f irst symptom appeared. Because of his young age Marques could not get vaccinated against the flu.

This tragedy has made Marques' mother and grandfather crusaders for yearly influenza vaccinations. Today, every adult and child in their family gets vaccinated against the flu.

On the morning of Saturday, February 28, 2004, 4½-year-old Amanda Kanowitz developed a cough and a mild fever. She stayed home and spent the day playing her favorite games with her family. The next morning, she began vomiting, but appeared to have nothing more than a typical virus.

By Sunday evening, Amanda appeared weak and her lips started to look gray. Amanda's mother called the family doctor, who told her that she had received over 60 calls that weekend about the same virus, and that Amanda would be okay as long as she stayed hydrated. The doctor recommended that Amanda only drink several sips of water at a time, and that her parents should make sure she continued to urinate.

At 3:30 a.m., Amanda woke her parents because she was concerned that she had drank an entire cup of water, instead of just taking sips. She then told them she had a stomachache and urinated in the bathroom.

Just four hours later, at 7:30 a.m., Amanda's parents found her lifeless in her bed.

To honor Amanda's memory, the Kanowitz family has established the Amanda Kanowitz Foundation, which is focusing on research to identify which other children should be considered high-risk for such sudden, extreme reactions to the flu and other infectious diseases. For more information, please visit http://www.amandakfoundation.org.

On the afternoon of January 28, 2004, 3½-year-old Emily Lastinger took a long nap and began to show signs that she was feeling ill. Strep throat had been circulating around her preschool, so Emily's parents kept her home from school and took her to see her doctor to make sure she was ok. However, a nurse performed a nasal swab test on Emily and determined she had the flu. She was given anti-viral medication in the hope that it would lessen the severity of the illness, and her parents were told to keep her hydrated and to control her fever.

On that Friday and over the course of the weekend, Emily became progressively worse. Her fever spiked and she began to vomit. However, Emily's pediatrician reassured her parents that these symptoms were a normal part of the flu and to just continue to make sure she stayed hydrated. Throughout the weekend, Emily continued to vomit and had trouble holding down fluids. Her parents again contacted the pediatrician's office, but they were reassured the symptoms were normal and were told to bring her in on that Monday if they were still concerned.

Emily did not improve over the weekend so on the morning of February 2, 2004, Emily's parents scheduled a doctor's appointment for later that day. The physician instructed them to administer fluids every 15 minutes until Emily was brought in to the office. After she was bathed and dressed for the doctor's office, Emily laid down in her parents' bed to rest and watch TV. She was found lifeless 15 minutes later.

Once her parents found Emily, they immediately began to administer CPR. Forty-five minutes later in the emergency department, doctors were able to get her heart started and then transferred Emily to a local children's trauma center. For 12 hours, doctors tried to fully revive her but the damage to her system was too great. Emily died later that evening.

The autopsy revealed that in addition to influenza, Emily had pneumonia with a painful complication called an empyema (a collection of pus or fluid in the cavity between the lung and surrounding membrane). Emily had not been vaccinated against the flu.

On the evening of October 30, 2009, previously healthy 7-year-old Trevor Ron Lin developed a cough. A day earlier, his 11-year-old sister, Ashley, had complained about shortness of breath that had stopped her while walking to the bus after school.

Both children's coughs remained mild that night and improved the next evening while trick-or-treating. Then on that third day, during the early hours of November 1, Trevor developed a seal-like barking cough, along with shortness of breath and fever. His father, a general surgeon, brought him to the bathroom and turned on the shower to allow the steam to resolve his symptoms. But these coughing episodes recurred every hour for the next three hours. On his third recurrent episode, his father, with concern for croup, urgently drove Trevor and his other two children together to the emergency room at the region's premier hospital.

The ER physicians agreed with the presumptive diagnosis of croup and treated Trevor accordingly with a nebulizer and one dose of intravenous steroids. The diagnosis of novel H1N1 influenza virus, or swine flu, was entertained but the ER physicians interpreted the guidelines from the Centers for Disease Control and Prevention (CDC) to mean that only high risk patients (children with co-morbidities or pregnant women) were eligible for anti-viral therapy such as oseltamivir (Tamiflu). During the ER visit, Trevor developed another episode of shortness of breath and had a fever of 103.7 degrees, with his heart rate increasing to an abnormal rate of more than 120 beats per minute. But his blood oxygen saturation levels remained normal at 97 percent. No chest x-ray or lab tests were performed.

Later during the ER visit, Trevor felt and looked better and wanted to go home along with his sister, Ashley, who had also been evaluated in the ER, but was feeling much better. Their middle brother, Ryan, had no symptoms.

The children went home and Trevor's symptoms improved. The next morning, he coughed only rarely, and had no problem breathing. However, the next afternoon on November 2, Ashley observed Trevor walking unsteadily at home and fell. Ashley ran over to find his lips and fingers blue. Despite resuscitation efforts and ambulance transportation to the nearest ER, Trevor was pronounced dead within two hours after his collapse.

His father discussed the case with a CDC physician who agreed that Trevor had a swine flu-related death. Trevor had not been vaccinated against H1N1 influenza because at the time the vaccine was not available in his community.

Trevor's father is currently campaigning for improved criteria for the health care practitioner evaluation of and hospitalization of children with influenza in order to minimize the numbers of previously healthy children who die from influenza after being evaluated recently by a health care practitioner. He plans on establishing a foundation in Trevor's name to encourage physician groups to provide working guidelines expeditiously despite having incomplete information during medical crises.

On February 8, 2005, 15-year-old Martin McGowan took an afternoon nap before trying out for the high school baseball team. His mother noticed that he looked a little under the weather, but Martin insisted that he felt fine – there was no way he would miss the highly-anticipated tryouts. Martin attended the baseball tryouts, but was exhausted afterwards. He also complained that his legs hurt from running. When Martin got home, he watched a little TV and went to bed.

The next morning at 2:30 a.m. Martin's mother heard him vomiting in the bathroom. He had a fever of 102 degrees. His mother gave him some medicine and he went back to bed. Martin later awoke at 4:30 a.m. and began to vomit once again. The pain in his legs had also increased. In addition to giving Martin plenty of fluids, his mother tried easing the pain in his legs by giving him a warm bath and applying ointment to the area, but nothing seemed to work. As the aching in his legs worsened, Martin's mother called the doctor who suggested that either Martin come in for an appointment that afternoon or his mother take him to the emergency room. Martin said he needed to go to the emergency room.

When he arrived at the hospital, the ER doctor took his vitals and did an initial evaluation. By this time, Martin's lips were white so they administered an IV. Martin was tested for influenza, which came back positive. He was also diagnosed with Compartment Syndrome – a disease that attacks the muscles, limiting blood circulation and causing severe pain. The intense running that Martin had done the night before escalated his condition from muscle aches to Compartment Syndrome in his legs. The doctor explained that if the blood flowing to Martin's legs ceased for an extended period of time, they might have to amputate his legs. Martin needed to be operated on as soon as possible.

Martin was taken into surgery that afternoon. However, during the surgery, his heart stopped beating. Doctors attempted to revive him but they were unsuccessful.

On February 9, 2005, Martin died of complications from influenza just 24 hours after his first symptom appeared. Martin had not been vaccinated against the flu.

In memory of Martin, the McGowan family has established a Scholarship Fund to coincide with Martin's love of baseball. The family has set up the M.A.R.T.I.N. (May All Receive Their Immunizations Now) Flu Foundation. The non-profit organization's mission is to provide information about the misconceptions of the influenza virus so that individuals understand the importance of immunization. The foundation achieves its mission by educating parents, children and athletic groups about the seriousness of the flu and its complications. For more information, please visit http://www.martinflufoundation.org.

In early December 2003, 6½-month-old Ian Moise began showing signs of being sick. He awoke from his morning nap and vomited. His parents took him to the pediatrician and were told that it appeared that Ian had the flu. The pediatrician said that if his symptoms did not improve to schedule a follow-up visit. As the evening wore on Ian's breathing became labored and his temperature increased. His parents decided to take him to an urgent care facility that specializes in children. That doctor told them that Ian had tested negative for respiratory syncytial virus (RSV), but tested positive for influenza. His parents were told to treat his symptoms and follow up in 48 hours if he did not show signs of improvement.

After a long night Ian's parents thought he seemed to be getting better. His breathing was not labored; rather it sounded more like a sigh. His temperature had also dropped. They thought the worst was over; however, Ian went into respiratory arrest on that Wednesday afternoon. They administered CPR and Ian was transported to the hospital. The doctor and staff worked to revive him, but all of their efforts failed.

Ian died on December 17, 2003 of complications from Influenza A, approximately 30 hours after he showed his first symptom of being sick. Ian and his two older brothers, Sean and Ryan, had received the first of two doses of the influenza vaccine two weeks prior to Ian becoming sick.

In memory of Ian, the Moise family has established Ian's Rainbow Flu Foundation, which is helping to educate people about the seriousness of influenza. For more information, please visit http://www.iansrainbow.org.

During the evening of December 20, 2003, 15-month-old Breanne Palmer developed a slight fever and began to show symptoms similar to her brother who had recently been diagnosed with influenza. The next morning, Breanne's fever rose to 101.5° F. Her parents took her to the pediatrician where the influenza diagnosis was made. Breanne was given antibiotics and sent home.

After visiting the doctor, Breanne took a long nap and her temperature began to slowly come down. Her parents continued to monitor her condition and give Breanne medication for her fever. When Breanne went to bed that night her temperature was almost normal. However, as the night wore on, Breanne's temperature climbed again very rapidly reaching 105.5° F. Her parents put Breanne in a bath to help bring down her fever, but she began to have difficulty breathing so they called 911.

At the hospital, Breanne's temperature rose to 107° F. Her temperature was brought down by the doctors in the emergency room, but Breanne had to be transferred to another hospital for more intensive care. A special life-support machine was needed as the virus began to attack Breanne's heart and brain stem. However, after being transferred to yet another hospital, doctors told Breanne's parents that the damage to her young body was too extensive. There was nothing the life-support machine could do. Breanne died in her mother's arms on December 23, 2003 from Influenza A.

Breanne's parents tried to get her vaccinated against the flu in early December but because she was diagnosed with an ear infection at the time her pediatrician would not vaccinate her.

On the evening of Sunday, February 15, 2009, 13-year-old Brittney started experiencing cold-like symptoms: cough, sore throat and congestion. These symptoms continued over the next 48 hours.

On that Tuesday, Brittney felt well enough to attend school. She loved school and being with her friends. She even went to gymnastics that afternoon. But, by that Wednesday, Brittney began complaining that it hurt to breath and that she was not able to take a deep breath. She also began running a fever of 103 degrees. Her father took her to a local urgent care and the physician recommended cough syrup, a fever reducer, fluid and rest. Her father was instructed that if her symptoms worsened to make an appointment to see her pediatrician. The following day, her breathing became even more labored. She was taken to the pediatrician who immediately had Brittney transported by ambulance to the local hospital. At the hospital, physicians felt her condition was deteriorating so quickly that it would be best to transport her again to a nearby children's hospital. Brittney was placed into a medically induced coma due to a collapsed right lung. She was intubated and then transferred to the pediatric ICU of the children's hospital. Upon arrival at the hospital, Brittney went into cardiac arrest. After 50 minutes of CPR, the staff was able to resuscitate her and her heart began beating again. On February 20, 2009 she was placed on an ECMO machine, which oxygenates the body. However, it was determined that her brain had sustained injury and she was pronounced “brain dead" and taken off life-support.

An autopsy determined her death to be from cerebral herniation, cardiac arrest, and respiratory distress syndrome due to Influenza B.

Prior to her illness, it was never suggested that Brittney receive a flu vaccine. She was a very happy, healthy child with no history of chronic illness. She was athletic and actively involved on the community's football/cheer team.

In memory of Brittney, the family advocates on the importance of being immunized against the flu every year, and educates about other preventative measures to take to help avoid getting influenza.

During the fall of 2001, Antonio celebrated his first birthday. Several weeks prior he had been hospitalized with a respiratory illness that made his breathing extremely labored and made him excessively dehydrated from fever and vomiting. Antonio spent several days in the hospital where he was surrounded by an oxygen tent and provided with treatments to aid with his breathing, which fortunately he responded well to and was able to go home for close follow-up with his pediatrician.

That November Antonio fell ill again. His mother became very concerned about his condition – throughout the day he vomited and had a very high fever. As the night wore on, he seemed to become more listless, but early the next morning Antonio's mother thought his fever had finally broken. She called the pediatrician to say he felt cold and clammy, but still so very listless.

The pediatrician directed his parents to rush Antonio to the hospital. Once in the emergency room, he was given oxygen and intravenous fluids. While in the hospital, Antonio's parents learned that being cold and clammy was not a sign the fever had broken, but a dangerous sign that his blood pressure was too low. He was placed in a crib with an oxygen tent and every hour, 24 hours a day a technician provided him with breathing treatments. Three days later Antonio was discharged to a very nervous set of parents with instructions about how to assess his breathing function in the event that he became ill again. Fortunately, Antonio made it through the rest of that flu season without any major illnesses.

Flash forward one year to the impeding flu season. Antonio's mother placed a call to the pediatrician to inquire about his need for a flu shot. She was informed that there was a shortage and the vaccine was available only for high risk children. His mother explained that Antonio was hospitalized twice the year before and she thought he might be high risk. It wasn't until this time that she was informed that Antonio had been hospitalized due to complications from the flu, and because he was also recently diagnosed with asthma he should receive the flu vaccine. This was the first time his parents learned that Antonio's hospitalization was related to influenza.

Today, Antonio is a healthy school-age child who gets vaccinated against influenza every year, as does his entire family. His parents realize that many families do not recognize how quickly influenza can escalate into a serious illness and urge all of their friends and family members to receive annual vaccinations.

During January 2002, 4½-year-old Jessica Stein and her brother, Eric, caught a virus that was going around their preschool. Like many of their fellow classmates and even some teachers, Jessica and Eric missed a few days of school, but recovered shortly thereafter.

By the end of the month, Jessica had completely resumed her daily activities. She attended a birthday party and played with her friends at a local park. She had begun napping in the afternoons, which was unusual for her, but otherwise appeared healthy and happy.

On that Wednesday evening following the birthday party, Jessica developed a mild fever and began vomiting. Her parents kept her home from school the next day. When they contacted her doctor's office, the nurse said Jessica had likely suffered a relapse from her previous illness, but she did not need to see the doctor. By that Friday, her fever began to subside and she somewhat regained her appetite, although, she was still weak, very tired, and fussy. Her breathing became labored that night and her hands and feet were cold. Jessica's parents contacted her doctor again, and he advised them to bring her to the emergency room in case she had become dehydrated and required an IV.

The doctors ran various tests on Jessica, and a pediatric cardiologist was called. After several hours, they determined her heart was a little enlarged, but it beat strongly. Jessica's parents were to be allowed back into the examination room to see her. Five minutes later, Jessica's heart stopped beating. Doctors attempted to revive her, but were unsuccessful.

On February 2, 2002, Jessica died of viral myocarditis. An autopsy was not conducted to determine what type of virus caused Jessica's ultimate death; however, viral myocarditis is linked to Coxsackie B and adenoviruses and can also result from the flu.

On the afternoon of February 2, 2003, 5½-year-old Alana Yaksich spent the day with her parents and brothers watching movies, eating sundaes and playing. Although she had a low-grade fever from a recent sore throat (for which she had finished a course of antibiotics), Alana enjoyed the afternoon feeling healthy, surrounded by her family. Later that evening, Alana developed a 106° F fever and was rushed to the emergency room.

Within 24 hours of her arrival at the local hospital, Alana died of flu-related complications that caused swelling and injury to her brain.

Because of this tragedy, Alana's parents have established ALANA'S Flu Foundation, which educates the public about the importance of yearly flu vaccinations. For more information, please visit http://www.alanasflufoundation.org/.